The present study aims to design and validate a blockchain-based human resource management practices model and to investigate how the model factors affect each other and practical solutions for the development of human resource management in the education organization. The present study was conducted with a combined approach. In the qualitative part, using the data theory method of the foundation and in-depth interviews with 12 experts, the model of blockchain-based human resource management practices was designed and validated. Then, in the second step, using the technique of confirmatory factor analysis and modeling of structural equations among 300 managers, deputies and experts of education departments of Kohkiluye and Boyer-Ahmad provinces, the resulting model was fitted, validated and tested. In the qualitative part of the model, consisting of two main themes and six sub-themes for causal conditions, one main theme and two sub-themes for background conditions, one main theme and four sub-themes for the central category, one main theme and four sub-themes for the interventionist conditions, one main theme and 6 sub-themes for strategies and 4 sub-themes for outcomes were obtained. The results of the quantitative section showed the significance of the relationships between the research variables. In this study, the causal conditions (information technology factors and recruitment process) were identified as a central category (strategic development of human resource management with blockchain technology); Affects and in this impact and impression; Background conditions (design of financial mechanisms and design of legal mechanisms); Interfering conditions (barriers to the use of technology); Are involved and strategies such as (area of ​​staffing); It can help achieve outcomes (strategic, organizational, information and technological implications).